TB-500
A physician-prescribed, compounded peptide based on a fragment of thymosin beta-4, studied in the lab and in animals for wound healing — with licensed provider oversight from intake through every refill.
Billed monthly. Includes everything.
HSA/FSA cards accepted
Prescription required. A licensed provider will review your information and prescribe only if medically appropriate. TB-500 is not FDA-approved, and compounded medications are not FDA-approved.
Stylized vial for marketing purposes only
Important — please read before starting
- TB-500 is not an FDA-approved drug. No TB-500 product has been approved for any use in the United States.
- How it's available: In late October 2026, the U.S. Department of Health and Human Services (HHS) published a draft interim policy saying it does not intend to take enforcement action against state-licensed pharmacies and physicians that compound TB-500 for individual patients with a valid prescription, as long as ten conditions are met — including sourcing the ingredient from an FDA-registered manufacturer with a certificate of analysis showing identity, purity, potency, and contaminant testing; single-ingredient products; reporting serious side effects to FDA; and specific labeling. For TB-500, the policy covers only TB-500 acetate given as an injection under the skin or into a muscle. This is enforcement discretion, not FDA approval. The policy is not final: HHS is accepting public comments through November 13, 2026, and the policy may change.
- There are no published human studies of TB-500. Research is in the lab and in animals, and FDA reviewers have noted that human studies of the full thymosin beta-4 protein are not evidence for TB-500 itself.
- Athletes: TB-500 is on the World Anti-Doping Agency (WADA) prohibited list, and use can result in sanctions even if it was prescribed.
About TB-500
TB-500 is a synthetic peptide based on a short section of thymosin beta-4, a protein found in most human cells. Thymosin beta-4 binds to actin, a protein that forms part of each cell's internal scaffolding and helps cells move.
It has drawn interest for recovery because of laboratory and animal research on wound healing. At Vytora Health, TB-500 is offered only as a prescription compounded by a licensed US pharmacy, after review by a licensed provider.
Proposed mechanism
In laboratory and animal studies, thymosin beta-4 and fragments of it appear to influence cell movement, the growth of new blood vessels, and inflammation — processes involved in wound repair. Whether TB-500 does the same in people has not been studied.
What the research shows — and doesn't
Lab & animal research
Laboratory and animal studies have looked at wound and tissue repair, mostly using the full thymosin beta-4 protein or related fragments.
Human research
There are no published human studies of TB-500. Human trials of the full thymosin beta-4 protein do not show how TB-500 behaves in people.
Regulatory review
In July 2026 an FDA advisory committee voted 8–6 (1 abstention) to recommend TB-500 for the pharmacy compounding list, reviewed for wound healing. FDA staff had recommended against it, and final rulemaking is still pending.
Who it may be for — and who should not use it
May be considered for adults who:
- Are 18 or older
- Are interested in a recovery-focused peptide and understand there are no human studies yet
- Can complete a full medical history and stay in contact with their provider
- Are comfortable giving themselves a small injection
Not appropriate if you:
- Are pregnant, breastfeeding, or trying to conceive
- Have active cancer or a history of cancer
- Have had an allergic reaction to TB-500 or any ingredient in the preparation
- Are under 18
- Compete in sports with anti-doping testing
Your provider may identify other reasons TB-500 isn't right for you.
Administration, dosing & storage
TB-500 is given as a small injection under the skin (subcutaneous) or into a muscle (intramuscular) — the only routes the HHS policy covers. Your dose, schedule, and how long you take it are determined solely by your licensed provider based on your history and goals.
Under the HHS policy, TB-500 is dispensed on its own, not mixed with BPC-157 or other peptides in the same vial. Step-by-step injection instructions and all supplies come with every shipment. Store it exactly as your pharmacy label directs — compounded peptide vials are usually kept refrigerated (36°F to 46°F) and out of direct light, and should not be frozen — and follow the beyond-use date on the label.
How it works
STEP 1
Complete your online visit
Share your health history, medications, and goals.
STEP 2
Provider review
A licensed clinician from our provider network reviews and prescribes only if appropriate.
STEP 3
Pharmacy ships to you
A licensed US 503A pharmacy prepares your prescription and ships it cold-packed.
STEP 4
Ongoing check-ins
Message your care team anytime and report any side effects.
Included with every plan
Medication & all supplies
Physician consultation
Unlimited provider messaging
Free cold-packed shipping
Injection instructions
Progress tracking portal
Potential side effects & risks
Because TB-500 has not been studied in people, its side-effect profile is not known. Effects that may be expected with peptide injections include:
- Injection-site redness, swelling, itching, or bruising
- Headache, nausea, or dizziness
- Fatigue or flushing
Possible serious risks. FDA has noted that peptides like TB-500 may cause immune reactions, including allergic reactions, and that peptide impurities can be hard to characterize. Because thymosin beta-4 is involved in cell movement and new blood-vessel growth, there is a theoretical concern TB-500 could affect existing tumors — which is why it is not prescribed to people with cancer or a history of cancer.
Get emergency care right away if you have trouble breathing, swelling of the face, lips, tongue, or throat, widespread hives, a racing heartbeat, or feel faint after a dose.
Tell your provider about all medications, supplements, and medical conditions before starting. Little is known about interactions with other drugs. Report any side effects to your care team — your pharmacy is required to report adverse events. This is not a complete list of possible side effects.
Frequently asked questions
TB-500 is a synthetic peptide based on a short section of thymosin beta-4, a protein found in most human cells. Thymosin beta-4 binds to actin, a protein that forms part of each cell's internal scaffolding and helps cells move.
No. TB-500 is not FDA-approved for any use, and compounded medications are not FDA-approved finished drug products. In late October 2026, the U.S. Department of Health and Human Services (HHS) published a draft interim policy saying it does not intend to take enforcement action against state-licensed pharmacies and physicians that compound TB-500 for individual patients with a valid prescription, as long as ten conditions are met, including tested ingredients from an FDA-registered manufacturer, single-ingredient products, and reporting serious side effects to FDA. For TB-500, the policy covers only TB-500 acetate given as an injection under the skin or into a muscle. This is not an approval, and the policy could change, including after public comment closes on November 13, 2026. If it does, we will notify active patients.
Research on TB-500 is limited to laboratory and animal studies, mostly of wound and tissue repair, and many used the full thymosin beta-4 protein rather than TB-500 itself. There are no published human studies of TB-500, and human trials of full thymosin beta-4 do not show how TB-500 behaves in people. Benefits in people have not been proven.
TB-500 is given as a small injection under the skin or into a muscle. Every shipment includes supplies and step-by-step instructions, and your care team can walk you through your first injection.
Not in the same product. The HHS policy covers only single-ingredient products, so blends that mix TB-500 with BPC-157 or other peptides are not offered. Your provider will decide whether taking more than one peptide as separate prescriptions is appropriate for you.
$229/month on a month-to-month plan, $209/month on a 3-month plan (billed $629 every 3 months), or $194/month on a 6-month plan (billed $1,169 every 6 months). Price includes medication, physician consultation, supplies, shipping, and unlimited provider support. This is a recurring subscription. Your card is charged automatically each billing cycle until you cancel. Cancel anytime by contacting support@vytorahealth.com.
TB-500 is typically prescribed for a defined course rather than indefinitely. The length of treatment, and whether to repeat it, is decided by your licensed provider based on your goals and how you respond. Talk to your provider before stopping or extending treatment.
Because TB-500 has not been studied in people, its side-effect profile is not known. Effects that may be expected with peptide injections include injection-site redness, swelling, itching, or bruising; headache, nausea, or dizziness; fatigue or flushing. FDA has noted that peptides like TB-500 may cause immune reactions, including allergic reactions, and that peptide impurities can be hard to characterize. Seek emergency care for trouble breathing, facial or throat swelling, or widespread hives. Report all side effects to your provider.
TB-500 is not appropriate if you are pregnant, breastfeeding, or trying to conceive; have active cancer or a history of cancer; have had an allergic reaction to TB-500 or any ingredient in the preparation; are under 18; or compete in sports with anti-doping testing. Your provider will review your full history and may identify other reasons it isn't right for you.
Possibly. Your provider will review everything you take — including GLP-1 medications, other peptides, NAD+, other prescriptions, and supplements — before prescribing. Little is known about TB-500 drug interactions, so always keep your care team updated on any changes.
If you are subject to anti-doping testing, we do not recommend it. TB-500 is on the World Anti-Doping Agency (WADA) prohibited list, and use can result in sanctions even if it was prescribed.
Your prescription is prepared by a licensed US 503A compounding pharmacy and shipped free in discreet, cold-packed packaging with all supplies. Store it exactly as your pharmacy label directs — compounded peptide vials are usually kept refrigerated (36°F to 46°F), out of direct light, and never frozen — and follow the beyond-use date on the label.
No. Insurance is never required. Pricing is all-inclusive — medication, physician consultation, supplies, shipping, and unlimited support. You can also pay with an HSA or FSA card.
Yes. TB-500 is available in all 50 US states and Washington, D.C. through our network of licensed compounding pharmacy partners, if a provider determines it is appropriate for you. Contact support@vytorahealth.com with any questions.
In most states, treatment can begin without a video visit. In Kansas, Louisiana, Mississippi, New Mexico, and West Virginia, a brief video or audio visit is required before starting treatment.
Exploring other peptide therapies? See all peptides, or visit our FAQ.
Clinical oversight by Wasef Health, PC and Arora Health and Aesthetics
All prescribing decisions are made solely by licensed clinicians with Wasef Health, PC or Arora Health and Aesthetics. Information on this page is for educational purposes and does not constitute medical advice. Regulatory information current as of November 2026.
Ready to get started?
Answer a few questions and a licensed provider will review whether TB-500 is right for you.
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Prescription required. A licensed healthcare provider will review your information and prescribe only if medically appropriate. Compounded medications are not FDA-approved finished drug products, have not been evaluated by the FDA for safety, efficacy, or quality, and may differ from FDA-approved drugs. Results may vary. Individual results are not guaranteed.
Stylized vial for marketing purposes only; image does not reflect the actual label or size of a prescription vial. Compounded medications are prepared by licensed US pharmacies for individual patients, are not FDA-approved, and are not brand-name or generic versions of any FDA-approved drug.
Vytora Health provides access to telehealth services connecting users with licensed healthcare professionals. Vytora Health does not practice medicine and does not guarantee that a prescription will be issued. All treatment decisions are made solely by the licensed clinician.